Purely imaginary roots under reverse-reaction removal

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Let GG be a reaction network containing the motif

y⇄Y→y′,y\rightleftarrows Y\to y',

where YY appears in no other complex. Let p(h,ℓ)p_{(h,\ell)} and p(h,ℓ′)′p'_{(h,\ell')} be the reduced characteristic polynomials of GG and the network obtained by removing Y→yY\to y, with h∈R>0nh\in\mathbb{R}^n_{>0}, ℓ∈R>0m\ell\in\mathbb{R}^m_{>0}, and ℓ′∈R>0m−1\ell'\in\mathbb{R}^{m-1}_{>0}. Purely imaginary-root equivalence conjecture. The polynomial p(h,ℓ)p_{(h,\ell)} has purely imaginary roots for some (h,ℓ)∈R>0n×R>0m(h,\ell)\in\mathbb{R}^n_{>0}\times\mathbb{R}^m_{>0} if and only if p(h,ℓ′)′p'_{(h,\ell')} has purely imaginary roots for some (h,ℓ′)∈R>0n×R>0m−1(h,\ell')\in\mathbb{R}^n_{>0}\times\mathbb{R}^{m-1}_{>0}. Such roots are relevant because they are necessary for the Hopf-bifurcation criterion, while the conjecture itself remains unproved.

References

Primary source

Elisenda Feliu and Nidhi Kaihnsa, “Network reduction and absence of Hopf Bifurcations in dual phosphorylation networks with three Intermediates”, arXiv:2405.16179 (2024).

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