3 problems
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Connectedness of multistationarity regions for weakly and strongly irreversible phosphorylation networks
For each , consider the weakly and strongly irreversible -site phosphorylation networks and their parameter regions of multistationarity. Connectedness conjecture. The…
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Path-connectedness of the full multistationarity region for strongly irreversible phosphorylation cycles
For a fixed , consider the -site phosphorylation cycle with Michaelis–Menten phosphorylation steps, reaction-rate constants , and parameters . The ful…
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Conjecture that the multiple futile cycle has maximally many positive steady states
Sharpness conjecture. The upper bound can be attained for suitable parameter values.