Necessity and sufficiency of D-unstable cores for network instability

A DD-unstable core is a DD-unstable Child-Selection matrix S[κ]\mathbb{S}[\pmb{\kappa}] such that none of its principal submatrices are DD-unstable. A network is said to admit instability when it possesses such an instability-inducing mechanism. D-unstable core conjecture. A network admits instability if and only if it possesses DD-unstable cores. The context states that DD-unstable cores are sufficient for a network to admit instability; the conjecture is that they are also necessary. Its resolution is not established in the supplied text.

References

Primary source

Alexander Blokhuis, Peter F. Stadler and Nicola Vassena, “Stoichiometric recipes for periodic oscillations in reaction networks”, arXiv:2508.15273 (2025).

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