Necessity and sufficiency of D-unstable cores for network instability

A DD-unstable core is a DD-unstable Child-Selection matrix S[κ]\mathbb{S}[\pmb{\kappa}] such that none of its principal submatrices are DD-unstable. A network is said to admit instability when it possesses such an instability-inducing mechanism. D-unstable core conjecture. A network admits instability if and only if it possesses DD-unstable cores. The context states that DD-unstable cores are sufficient for a network to admit instability; the conjecture is that they are also necessary. Its resolution is not established in the supplied text.

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Primary source

Alexander Blokhuis, Peter F. Stadler and Nicola Vassena, “Stoichiometric recipes for periodic oscillations in reaction networks”, arXiv:2508.15273 (2025).

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