Triangular Gröbner-basis conjecture for chemical reaction networks
Triangular Gröbner-basis conjecture for chemical reaction networks
Consider a chemical reaction network (CRN) whose steady-state ideal satisfies Assumptions 1–3: mass-action kinetics, inclusion of conservation laws, and absence of independent subnetworks. Let the system have variables , and let be the extension field of generated by the coefficients of its equations. Triangular Gröbner-basis conjecture. There exists a permutation such that, after re-labelling the variables
the reduced Gröbner basis of the steady-state ideal, computed in the lexicographic order
has the triangular shape
where and, for every , . Thus the first polynomial is univariate in , and each remaining polynomial is linear in its corresponding variable with coefficients polynomial in . The conjecture is motivated by numerical searches that found no CRN satisfying Assumptions 1–3 while violating the stated triangularity; the supplied context also says that triangularity is proved under a strengthened set of hypotheses, leaving the conjecture itself unresolved.
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Primary source
Paola Ferrari, Sara Sommariva, Michele Piana, Federico Benvenuto and Matteo Varbaro, “When algebra twinks system biology: a conjecture on the structure of Gröbner bases in complex chemical reaction networks”, arXiv:2501.12233 (2025).
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