Leak-addition conjecture for unidentifiable linear compartmental models

Let M\mathcal{M} be an unidentifiable linear compartmental model. Leak-addition conjecture. If one leak is added, the resulting model M~\widetilde{\mathcal{M}} is also unidentifiable. This is equivalent to the assertion that removing a leak from an identifiable model preserves identifiability, in the corresponding setting. The paper proves special cases, but the general conjecture remains open.

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Primary source

Patrick Chan, Katherine Johnston, Anne Shiu, Aleksandra Sobieska and Clare Spinner, “Identifiability of Linear Compartmental Models: The Impact of Removing Leaks and Edges”, arXiv:2102.04417 (2021).

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