Dividing-edge conjecture for linear compartmental models

Let M\mathcal{M} be a strongly connected linear compartmental model that is generically locally identifiable, with singular-locus equation ff. An edge jij\to i is dividing if its parameter kijk_{ij} divides ff. Dividing-edge conjecture. If jij\to i is a dividing edge of M\mathcal M, and the model M\mathcal{M}' obtained by deleting the edge jij\to i is strongly connected, then M\mathcal{M}' is unidentifiable. The conjecture is motivated by the converse of the known result that deleting non-dividing edges preserves generic local identifiability. It is proved in cases where deleting the edge increases the shortest input-output path length, but the general claim remains open.

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Primary source

Patrick Chan, Katherine Johnston, Anne Shiu, Aleksandra Sobieska and Clare Spinner, “Identifiability of Linear Compartmental Models: The Impact of Removing Leaks and Edges”, arXiv:2102.04417 (2021).

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