Quasi-stationary distributions in fixed and random vector-population epidemic models

Let nn be the population-size scaling parameter, let Ihn(t)I_h^n(t) and Ivn(t)I_v^n(t) denote infected hosts and infected vectors, and let R0\mathcal{R}_0 be the basic reproduction number. Consider both the model with fixed host and random vector population sizes and the model with fixed host and vector population sizes. Quasi-stationary distribution conjecture. For large nn: (i) if R0<1\mathcal{R}_0<1, (Ihn(t),Ivn(t))(I_h^n(t),I_v^n(t)) approaches (0,0)(0,0) exponentially fast as tt\to\infty; (ii) if R0>1\mathcal{R}_0>1, the model with fixed host and random vector population size has no quasi-stationary distribution; and (iii) if R0>1\mathcal{R}_0>1, the model with fixed host and vector population sizes admits a quasi-stationary distribution that can be approximated by a normal distribution with mean nEenE^e and variance nΣn\Sigma^* as specified in the source. The claim contrasts the effects of random and fixed vector population sizes on long-term epidemic behavior. The preceding discussion explains the absence of a quasi-stationary distribution in the random-vector case and the approximate normal law in the fixed-vector case; no separate resolution status is given.

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Primary source

Xin Liu, Anuj Mubayi, Dominik Reinhold and Liu Zhu, “Approximation Methods for Analyzing Multiscale Stochastic Vector-borne Epidemic Models”, arXiv:1806.03778 (2018).

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