Feinberg's persistence conjecture for weakly reversible reaction systems

Let NN be a confined, weakly reversible mass-action ordinary differential equation system, and let M(N)\mathfrak M^\ell(N) denote its associated differential inclusion. A differential inclusion is persistent when its trajectories do not approach the boundary of the nonnegative state space. Feinberg's persistence conjecture. For every confined, weakly reversible mass-action ODE system NN, the differential inclusion M(N)\mathfrak M^\ell(N) is persistent. Persistence is a central unresolved property in reaction network dynamics; the paper states that this conjecture remains open.

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Primary source

Manoj Gopalkrishnan, Ezra Miller and Anne Shiu, “A Projection Argument for Differential Inclusions, with Applications to Persistence of Mass-Action Kinetics”, arXiv:1208.0874 (2013).

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