Criterion for moderate infection under increasing division rates
Criterion for moderate infection under increasing division rates
Let be the total quantity of parasites at time , let be the set of cells at time , let , and let denote the parasite quantity in cell . Assume that the division rate is increasing, and write
Let be the parasite-growth drift and let be the random fraction governing parasite sharing. Criterion for moderate infection. (i) If
then, almost surely,
(ii) If
then for every ,
This criterion separates moderate infection, where the proportion of cells carrying at least parasites vanishes as tends to infinity, from persistent infection in a positive proportion of cells. It is proposed using an approximation of the evolution of the cell proportions and extends the recovery criterion from the constant-division-rate case; the source presents it as a conjectural criterion rather than a proved result.
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Primary source
Vincent Bansaye and Viet Chi Tran, “Branching Feller diffusion for cell division with parasite infection”, arXiv:1004.0873 (2010).
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